Mapping the Early Cortical Folding Process in the Preterm Newborn Brain
نویسندگان
چکیده
منابع مشابه
Mapping the early cortical folding process in the preterm newborn brain.
In the developing human brain, the cortical sulci formation is a complex process starting from 14 weeks of gestation onward. The potential influence of underlying mechanisms (genetic, epigenetic, mechanical or environmental) is still poorly understood, because reliable quantification in vivo of the early folding is lacking. In this study, we investigate the sulcal emergence noninvasively in 35 ...
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Introduction In the adult brain, the cortical sulci morphology is highly variable among individuals [1], whereas the primary folds (called sulcal roots) are assumed to develop in a stable way during intra-uterine life [2]. So far, several hypotheses have been conducted on the factors that underlie this folding process, like the mechanical tension from white matter fibers [3], but quantitative...
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To study the patterns of supraspinal pain processing in neonates, we hypothesized that acute pain causes haemodynamic changes associated with activation of the primary somatosensory cortex. Forty preterm neonates at 28-36 weeks of gestation (mean=32.0) and at 25-42 h (mean=30.7) of age were studied following standardized tactile (skin disinfection) and painful (venipuncture) stimuli. Changes in...
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Very preterm birth (less than 32 weeks completed gestation) coincides with a rapid period of brain growth and development. Investigating the changes of certain brain regions may allow the development of biomarkers for predicting neurological outcome. The prefrontal cortex, associated with the executive function, undergoes major changes during the last 10 weeks of pregnancy, and therefore its de...
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In the human brain, the morphology of cortical gyri and sulci is complex and variable among individuals, and it may reflect pathological functioning with specific abnormalities observed in certain developmental and neuropsychiatric disorders. Since cortical folding occurs early during brain development, these structural abnormalities might be present long before the appearance of functional sym...
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ژورنال
عنوان ژورنال: Cerebral Cortex
سال: 2007
ISSN: 1047-3211,1460-2199
DOI: 10.1093/cercor/bhm180